Paper and Presentations


SUNDAY, MARCH 13, 2011


ANDalyze founder Dr. Yi Lu speaking at PITTCON Sunday March 13th, 2011 at 1:20PM


Section 130-2 Paper Based Point-of-care Analytical Kits


Topic: A Simple Colorimetric “Dipstick” Test for a Broad Range of Targets in the

Environment and Medicine Based on Functional DNA Nanotechnology


Presenters: Dr. Yi Lu, University of Illinois at Urbana-Champaign, Seyed-Fakhreddin Torabi,& Debapriya Mazumdar, VP of Product Development, ANDalyze


Rapid detection of bacteria, viruses and biomarkers in patient fluid samples are of crucial importance in the field of clinical diagnostics. Paper, being relatively cheap and abundant, sustainable, disposable, and easy to use, store, transport, and modify, has been the focus of significant attention as a platform for the development of paper-based analytical devices. Paper is made up of hydrophilic cellulose fibers which impart it a unique property of being able to move fluids by capillary action without the need of power. Biorecognition molecules such as antibodies, enzymes, DNA, aptamers are physically immobilized onto the sensor surface via covalent or affinity attachment or entrapment techniques. Colorimetric detection has been most commonly used as it enables rapid analysis and does not require sophisticated equipment or trained personnel. The objective of this symposium is to provide an overview of recent developments and applications of lateral flow based paper sensors for various biosensing applications. The proposed speakers were determined based on their recent contribution towards the development, characterization and application of paper based sensor for point of care medical diagnostics. 

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